Overlapping Infection by Strongyloides spp. and Cytomegalovirus in the Immunocompromised Host: A Comprehensive Review of the Literature

Strongyloides and cytomegalovirus co-infections are rarely reported, even though they distinguished by high morbidity mortality, especially in immunocompromised hosts. We narratively reviewed the literature on reported cases of CMV immunosuppressed patients. Most occurred males with a median age 47 (IQR, 37–59). Strongyloides/CMV among hosts, solid organ transplants hematological or rheumatological diseases. patients underwent course steroid treatment before diagnosis co-infections. Other common immunomodulatory agents were tacrolimus mycophenolate. The first clinical manifestations mainly gastrointestinal, followed respiratory symptoms. was, most patients, co-infected an isolated reactivation, although manifested as hyperinfection syndrome. Ganciclovir ivermectin mainstays treatment. However, mortality this narrative review is around 52.4%. Interestingly secondary bacterial infections CMV/Strongyloides-infected